Solubilisation efficiency of Soluphor® P (2-pyrrolidone) for itraconazole was exploited for developing a self-emulsifying formulation. The objective of this study was to develop and evaluate self-emulsifying drug delivery system (SEDDS) for improving the delivery of a poorly water-soluble antifungal agent, itraconazole (ITZ).

Advancements in human knowledge across various scientific fields, including medical sciences such as vaccination, lifestyle, health, medical procedures, pharmacology, and up-to-date screening programs, have contributed to an increase in life expectancy

Drug resistance poses a challenge in managing microbial infections, highlighting the urgency to develop novel , effective antimicrobials. The natural environment is a proven source of novel antimicrobial agents

Rheumatoid arthritis (RA) has a 24-hour rhythm with a characteristic symptom of morning stiffness, which causes pain in the joints from late night to early morning.

Plasmodium parasites, which cause malaria, continue to pose a serious threat to global health, necessitating the continuous search for novel antimalarial agents. E

The target of most cancer chemotherapeutic agents is to drive cancer cells toward death, necessitating the need to find a fine balance between anti-apoptotic and pro-apoptotic proteins in maintaining cellular homeostasis. Any shift favoring the proapoptotic proteins is needed to drive cellular death in cancer chemotherapy.

Nanocrystal technology has showed significant potential for commercial applications and advancements as a novel pharmacological method to increasing the water solubility of certain poorly soluble medicines.

The transdermal drug delivery system is technique that provides drug through the intact skin. Skin penetration enhancement techniques have been developed to increase the bioavailability of drug substance.

Before the development of highly active antiretroviral medication, AIDS and related illnesses caused a great deal of suffering and death. All of the AIDS-related morbidities and mortality have considerably decreased thanks to modern medication, especially in industrialized nations.

Louse infestation is the poor personal hygiene and a blood feeding ectoparasitic insect of order ptrithirapetera. Inadequate access of water supply leads people to acquire communicable disease such as typhus and relapsing fever.